Palmitoylethanolamide PEA for nerve pain

Palmitoylethanolamide for Nerve Pain or Migraine (PEA).

Palmitoylethanolamide (PEA) is a glial cell modulator. Glial cells are Central Nervous System cells which release many inflammatory substances that act upon neurons, amplifying pain (Watkins and Maier, 2002). With time, PEA modulates (or tones down) overactive pain nerves into rest states.

PEA performs a great variety of biological functions related to chronic and neuropathic pain and inflammation, as demonstrated in clinical trials. These include peripheral neuropathies such as diabetic neuropathy, trigeminal neuralgia, chemotherapy-induced peripheral neuropathy, carpal tunnel syndrome, sciatic pain, osteoarthritis, low back pain, failed back surgery syndrome, dental pains, neuropathic pain in stroke and multiple sclerosis, chronic pelvic pain, post-herpetic neuralgia, burning mouth pain, burning feet  and vaginal pains.

Other Benefits:
•  PEA is the key to suppressing overactive mast cells. Mast cells release inflammatory histamine and cytokines into the body. The analgesic and anti-inflammatory nutraceutical PEA, holds great promise blunting the inflammatory response in the treatment of chronic pain states like interstitial cystitis, bladder pain and irritable bowel syndrome.
•  PEA can be taken simultaneously with other medicine.
•  There are no significant side effects

•  Compounded capsules are available now

.  Oral adhesive pastes and topical transdermal creams can also be prepared.